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العنوان
Pharmacological and Toxicological Studies on Syrian Cichorium intybus plant /
المؤلف
Saffaf, Bayan Abd Al Razzak.
هيئة الاعداد
باحث / بيان عبد الرزاق سفاف
مشرف / محمد عاطف أحمد شحاته
مشرف / أبو بكر يوسف الجندي
مشرف / عزيزة محروس محمد عامر
تاريخ النشر
2012.
عدد الصفحات
145 Leaves :
اللغة
الإنجليزية
الدرجة
ماجستير
التخصص
البيطري
الناشر
تاريخ الإجازة
1/1/2012
مكان الإجازة
جامعة القاهرة - كلية الطب البيطري - Pharmacology
الفهرس
Only 14 pages are availabe for public view

from 164

from 164

Abstract

The Cichorium intybus belongs to the family Asteraceae. The Cichorium intybus ethanolic extract contains carbohydrate, tannins, resin, saponins, alkaloids, and flavonoids as active constituents.
LD50 of ethanolic extract of Cichorium intybus orally administration in mice was 8700mg/kg.b.wtThe Cichorium intybus ethanolic extract at dose (870,435 mg/kg.b.wt), had antioxidant activity as well as hepatoprotective effect against CCL4 at rats , anti inflammatory, analgesic and diuretic effect but showed no effect on antipyretic at the same dose. Ithad stimulant followed by inhibition effect on the intestinal motilityand stimulant effect on the uterine contraction at estrus and late of pregnant. Orall administration for 2 month at dose (870 mg/kg b.wt), increased thePCV, neutrophiles, lymphocytes and liver enzymes, reducing the body weight, reducing the sperms count and increasing the percentage of dead and abnormal sperms at male of rats , The extract had anticancer effect on liver and colon but lesser effect on Breast cancer.