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العنوان
Effect of lipopolysaccharide preconditioning on human umbilical cord blood-derived endothelial progenitor cells
الناشر
Mai Samir Mostafa Riad
المؤلف
Riad , Mai Samir Mostafa
هيئة الاعداد
مشرف / Olfat Nouh Riad
مشرف / Dina Sabry Abd El-Fatah
مشرف / Mohamed Talaat Abd El Aziz
مشرف / Mai Samir Mostafa Riad
تاريخ النشر
2012
عدد الصفحات
124P:.
اللغة
الإنجليزية
الدرجة
ماجستير
التخصص
الطب (متفرقات)
تاريخ الإجازة
1/1/2012
مكان الإجازة
جامعة القاهرة - كلية الطب - Medical Biochemistry
الفهرس
Only 14 pages are availabe for public view

from 115

from 115

Abstract

Endothelial progenitor cells (EPCs), described in 1997 by Asahara
et al .,constitute a heterogeneous population of circulating cells in
peripheral blood. Their origin is found in multipleprecursors, such as
hemangioblasts, non-hematopoietic precursors, monocytic cells, or tissue-resident stem cells. Endothelial progenitor cells play an important role in
vascular repair and new vessel formation, because of their capacity to
proliferate, migrate, differentiate in vivo and in vitrointo endothelial
cells, and incorporate into the preexisting endothelium. Thus,
phenotypically, they have morphofunctional characteristics of both
hematopoietic and mature endothelial cells (Silva et al., 2012) .
The study included 50 samples of human umbilical cord blood
(hUCB) collected from women during normal labor andafter taken their
informed consent at the Obstetric and Gynecology Department Faculty of
Medicine, Cairo University. The work up of the endothelial progenitor
cells was performed at the Unit of Biochemistry andMolecular Biology
at The Medical Biochemistry Department, Faculty of Medicine, Cairo
University