الفهرس 
Screening and diagnosis of diabetes mellitus and its complications in pregnancy
Risk factors for GDMOnly 14 pages are availabe for public view
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Abstract
Diabetes mellitus increase the risk of both maternal and perinatal morbidity and mortality. Fetal macrosomia is one of the main perinatal complications in all types of diabetic pregnancy, especially in women with poor glycemic control. However strict glycemic control sometimes failed to prevent macrosomia.
Fetal growth in a diabetic pregnancy is a complex process and maternal metabolic parameters other than glucose levels should be addressed to reduce the risk of macrosomia in this group of patients. Serum lipid levels provide an attractive alternative.
Birth weight (BW) is an important predictive parameter for neonatal morbidity and mortality. Hence, accurate estimation of fetal weight may be a valuable tool for determining further obstetric management
This study was done to determine the association between maternal serum triglyceride levels and newborn weight and the predictive value of serum triglyceride levels (TG) for neonatal weight in pregnant diabetic women.
Seventy controlled pregestational diabetic pregnant women were selected for this work at 28 week of gestation from the patients attending the outpatient clinic of antenatal care of Ain Shams Maternity Hospital.
The following parameters were measured: fasting serum triglyceride, total cholesterol, LDL cholesterol and HDL cholesterol at 28 weeks of gestation. All subjects were followed until delivery. Information regarding time and mode of delivery and birth weight were obtained in all women. We used SPSS version 18.0 for Windows software, for statistical analysis.
There was a highly significant positive linear correlation between fasting serum triglyceride and neonatal birth weight. Maternal hypertriglyceridemia was a significant risk of having a macrosomic infant at term. A significant association between birth weight and HDL cholesterol in controlled diabetic pregnancies was found.
In our study, a highly significant positive linear correlation between fetal weight by ultrasonography at 28 week of gestation and fasting serum triglyceride was found. There was a significant negative linear correlation between HDL cholesterol and fetal weight by ultrasonography at 28 week of gestation.