الفهرس | Only 14 pages are availabe for public view |
Abstract The aim of the present study was to assess the relation of prolactin, ferritin and vitamin D levels as immunomodulatory markers in patients with rheumatoid arthritis. This study was conducted on 50 female subjects: 20 healthy subjects as a control group and 30 patients with RA selected from outpatient clinic of Rheumatology in Ain Shams University Hospital. Subjects enrolled into the study were classified into: Group A: 15 patients with active RA. Group B: 15 patients in remission of rheumatoid activity. Group C: 20 healthy subjects as a control group. The results were statistically analysed and we observed the following: Serum Prolactin: was significantly higher in patients with active RA than in normal healthy controls. Also we found that there was no statistical significant correlation between patients with +ve RF & PRL level in groups A & B. The same was also with ESR. Serum Ferritin: was significantly higher in patients with active RA than in group B and group C with highly statistically significant difference. Also, our results showed negative correlation with hemoglobin in patients with active RA and in patients in remission but statistically non-significant . Also there was no statistically significant difference between patients with +ve RF in groups A & B and ferritin level. The same is also with ESR. Serum Vitamin D: Hypovitaminosis D was more prevalent among active RA patients (group A) than the other two groups. Also, no significant correlation noted between vitamin D and ESR in the 3 groups. |