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العنوان
Study of Prolactin, Ferritin & Vitamin D as Immunomodulatory Markers in Patients with Rheumatoid Arthritis
المؤلف
Manal ,Mohammed Abdel Hamid Hassan
هيئة الاعداد
باحث / Manal Mohammed Abdel Hamid Hassan
مشرف / Mohammad Hesham El-Gayar
مشرف / Salwa Seddik Hosny
مشرف / Manal Mohammad Abu Shady
الموضوع
Rheumatoid Arthritis-
تاريخ النشر
2010
عدد الصفحات
264.p:
اللغة
الإنجليزية
الدرجة
ماجستير
التخصص
علم الغدد الصماء والسكري والأيض
تاريخ الإجازة
1/1/2010
مكان الإجازة
جامعة عين شمس - كلية الطب - Endocrinology
الفهرس
Only 14 pages are availabe for public view

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from 264

Abstract

The aim of the present study was to assess the relation of prolactin, ferritin and vitamin D levels as immunomodulatory markers in patients with rheumatoid arthritis.
This study was conducted on 50 female subjects: 20 healthy subjects as a control group and 30 patients with RA selected from outpatient clinic of Rheumatology in Ain Shams University Hospital. Subjects enrolled into the study were classified into: Group A: 15 patients with active RA. Group B: 15 patients in remission of rheumatoid activity. Group C: 20 healthy subjects as a control group.
The results were statistically analysed and we observed the following:
Serum Prolactin: was significantly higher in patients with active RA than in normal healthy controls. Also we found that there was no statistical significant correlation between patients with +ve RF & PRL level in groups A & B. The same was also with ESR.
Serum Ferritin: was significantly higher in patients with active RA than in group B and group C with highly statistically significant difference. Also, our results showed negative correlation with hemoglobin in patients with active RA and in patients in remission but statistically non-significant . Also there was no statistically significant difference between patients with +ve RF in groups A & B and ferritin level. The same is also with ESR.
Serum Vitamin D: Hypovitaminosis D was more prevalent among active RA patients (group A) than the other two groups. Also, no significant correlation noted between vitamin D and ESR in the 3 groups.