الفهرس 
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Abstract
Androgenetic alopecia (AGA), the most common type of baldness, is a hereditary thinning of the hair induced by androgen in genetically susceptible men that has its onset in late adolescence.
About 50% of male population show some degree of AGA around 50 years of age.
In androgenetic alopecia (AGA), dihydrotestosterone (DHT) bind to androgenic receptors in hair follicles of the scalp that triggers the genes accountable for gradual transformation of large terminal follicles to miniature ones.
There is relationship between Insulin resistance (IR) and Androgenetic alopecia (AGA) has been suggested.
Insulin resistance (IR) is an impaired biological response to a given concentration of insulin followed by increase insulin secretion with compensatory hyperinsulinemia, to maintain normal glucose and lipid homeostasis.
Insulin resistance is the underlying physiopathology of metabolic syndrome (MS), which is characterized by a combination of medical disorder that, when occurring together, increase risk of developing cardiovascular disease and diabetes.
The hyperinsulinemia secondary to insulin resistance may be a mechanism that later in life may lead to development of metabolic complications such as type 2 diabetes, hypertention and clinically evident atherosclerosis.
The aim of this study was to evaluate the possible association of male androgenetic alpecia (AGA) with insulin resistance (IR) and or metabolic syndrome.
This study was carried on thirty male patients suffering from different grades of AGA and ten male controls not suffering from AGA; they were selected from the Dermatology outpatient clinic of Alexandria main University Hospital. A blood sample was collected from each patient to measure lipid profile, fasting blood sugar, free testosterone, and fasting insulin
The result of this study showed a significant difference in the level of fasting insulin level, fasting blood sugar, and cholesterol level between patients and the controls groups and there level was significally higher in the patients group.
Also the study showed a significant difference in the waist circumference and the body mass index between patients and the controls groups. On the other hand, there was no significant difference in the level of the free testosterone between patients and the controls group.