الفهرس 
Cover Page Title in EnglishOnly 14 pages are availabe for public view
 |  | from | 170 |  |  |
| | | from | 170 | | |
Abstract
Experiment I: The objective of this experiment was to investigate the effect of anhydrous aluminum chloride on behaviour, productive performance, learning ability of rat’s offspring; biochemical changes as well as serum levels of adrenocortical hormones (corticosterone) of adult female rats; histopathological changes and residue in organs. The results revealed that:
1.Feeding time and drinking frequency increased significantly in rats treated with 3g/l anhydrous aluminum chloride than controls, also the standing time decreased significantly in rats treated with different doses of anhydrous aluminum chloride than the controls, moreover, the lying time increased non-significantly in rats treated with 2g/l anhydrous aluminum chloride than the other treated groups and controls. 2Licking frequency decreased significantly in all treated groups than controls and scratching frequency decreased nonsignificantly in rats treated with 2g/l and 3g/l anhydrous aluminum chloride than the controls, while the treatment had significant effect by reduction on movement, investigation of cage and investigation of trough frequencies than controls. 3.On the other hand, licking frequency of litters, nest building frequency and nursing time increased non-significant in rats treated with 2g/l anhydrous aluminum chloride (lowest dose) than controls, while the retrieving frequency showed non-significant effect by treatment 4. The present findings concerning the effect of last two weeks of pregnancy and lactation period on feeding time, drinking frequency and movement activities showed a gradual increase in the feeding time, drinking frequency (8.13+1.20min/hr and 0.76+0.15freq/hr) and movement activities throughout the experimental period with highest increase during last week of lactation. 5.Licking, scratching, investigation of cage and trough frequencies decreased gradually during experimental period with especially during the last week of lactation, while standing was higher during lactation period than during last two weeks of pregnancy and lying time was higher during last two weeks of pregnancy than during lactation period. 6.The effect of lactation period was discussed and reported that there was a significant gradually decrease in licking frequency of litters, nest building and retrieving frequencies and nursing time during lactation period (1st week 2nd week 3rd week). 7.The present results also deducted that the effect of period of day on feeding time, drinking frequency, licking and scratching frequencies, movement activities, investigation of cage and trough frequencies and also retrieving frequency was more clear during the late morning period (9-12 a.m.) as all these behavioural patterns were increased than any other period in the day, while the standing and lying time were increased during the early morning (6-9 a.m.) and late afternoon period (3-6 p.m.) than other periods of day. 8. However, the frequency of licking litters and nursing time were higher during early afternoon (12-3 p.m.) than any other periods of day, moreover, the nest building frequency was highest in early and late morning periods than other periods of day.
9Latency to closed arms was low in offspring of rats treated with 3.5g/l aluminum chloride and high in 2g/l anhydrous aluminum chloride.