الفهرس | Only 14 pages are availabe for public view |
Abstract Renal masses are being discovered with increasing frequency due to the large number of cross-sectional studies being performed in clinical practice. Accurate characterization of renal masses is essential to ensure appropriate case management and to assist in staging and prognosis (41). Accurate characterization of complex renal lesions is based primarily on the presence or absence of enhancement on contrast material enhanced Magnetic Resonance (MR) images. When such enhancement is present, it generally indicates a diagnosis of renal cell carcinoma (RCC) (excluding benign masses like angiomyolipomas and oncocytomas). With MR imaging, enhancement can be assessed by measuring signal intensity changes or evaluated visually with or without image subtraction (91). However, in view of recently reported concerns regarding the development of nephrogenic systemic fibrosis in patients with renal insufficiency who undergo contrast-enhanced MR imaging, there is increasing interest in assessing nonenhanced imaging modalities that might be useful for characterizing renal lesions (33).The aim of this study is to evaluate the role of contrast enhanced magnetic resonance imaging and the usefulness of diffusion weighted magnetic resonance imaging in differentiating benign from malignant renal masses and to assess the diffusion characteristics as well as apparent diffusion coefficient (ADC) values of different renal masses.In conclusion, breath-hold DW imaging could be easily added to a routine renal MR imaging protocol, is an accurate method for renal lesion characterization, and can yield useful information additional to that acquired with contrast-enhanced MR imaging. We recommend using high b values for better results. |