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العنوان
The Association Between E-selectin Gene
Polymorphism and Atherosclerosis in End-
Stage Renal Disease/
الناشر
Alaa Afif AbdelRaouf،
المؤلف
Alaa Afif ،AbdelRaouf
هيئة الاعداد
باحث / Alaa Afif AbdelRaouf
مشرف / Nadida Abdelhamid Gohar
مشرف / Nahla Aly Fawzy ،Fayek.
مشرف / Bahaa Eldeen Mostafa ،Zayed.
تاريخ النشر
2009.
اللغة
الإنجليزية
الدرجة
ماجستير
التخصص
جراحة
تاريخ الإجازة
1/1/2009
مكان الإجازة
جامعة القاهرة - كلية الطب - الجراحة
الفهرس
Only 14 pages are availabe for public view

from 136

from 136

Abstract

Atherosclerosis is the main cause of death and cardiovascular (CV)
complications in end-stage renal disease (ESRD). A possible explanation
is that decreased renal function may be associated with other nontraditional
risk factors, and genetic factors. This study involved 40 end
stage renal disease patients and 30 age- and sex- matched healthy control
subjects. All were subjected to Full history taking, full clinical
examination, kidney functions & genotyping of the ”Leu 554 Phe”
polymorphism in the E-selectin gene, Doppler examination of the carotid
artery (for the patient group only).
The CT (heterozygous) genotype is the more prevalent genotype in
our small studied groups and the presence of the T allele might not carry
the risk of atherosclerosis in ESRD patients.
Key words: Chronic kidney disease,
Atherosclerosis,
E-selectin.