الفهرس 
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Abstract
Obesity is a condition that represents a serious worldwide threat to public health and has been found to increase the risk of various comorbidities, including coronary heart disease and type-2 diabetes. Epidemiological studies have demonstrated that lifestyle choices, accumulated across the life course, greatly influence the risk of developing obesity. Obesity results from the interaction of many factors, including genetic, metabolic, behavioural and environmental influences. Obesity increases the risk for many chronic diseases, including hypertension, type II diabetes, gallbladder disease and coronary artery diseases (CAD).
Obesity can be divided into two principal types: 1) central or visceral, characterized by fat depots surrounding organs deep in the abdominal area, and 2) subcutaneous (SC), superficial fat depots under the skin which can occur anywhere.
Adipose tissue is an important source of cytokines, and adiposity contributes to the proinflammatory milieu. Serum cytokine levels are elevated in humans and animals with excess adiposity.
Approximately, 30% of circulating IL-6 is estimated to be from adipose tissue. Moreover, some reports have suggested that visceral adipose tissue secretes more IL-6 than subcutaneous adipose tissue.
C-reactive protein (CRP) has been used as an acute phase reactant and a marker of systemic inflammation. Morever, CRP has been recognized as a very useful and sensitive predictor of the future risk of myocardial infarction (MI) and stroke in the past several years. It is well known that CRP levels in adult subjects elevate with aging, excess of body mass index (BMI), and smoking. It has been proven that weight loss and the improvement of insulin resistance lead to decreases of CRP levels.
This study was conducted on 60 females patients 40 obese and 20 non obese serving as control.
All individuals included in this study will be subjected to the following:
1. Full history taking and clinical examination.
2. Anthropometric measurement {weight, Body Mass Index, waist circumference}.
3. Serum level of CRP by Enzyme Linked Immunosorbent Assay (ELISA).
4. Serum level of Interlokin-6 by Enzyme Linked Immunosorbent Assay (ELISA).
The results of this study showed that;
1. A statistically significant increase in the serum level of CRP in obese than in non obese individuals.
2. A statistically significant increase in the serum level of IL-6 in obese than in non obese individuals.
3. CRP showed the highest correlations with BMI followed by weight and waist circumference.
4. IL-6 showed the highest correlation with waist circumference followed by BMI and weight.