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العنوان
Evaluation of Infection and Antimicrobial Selection Patterns in Ain Shams University Neonatal Intensive Care Unit
المؤلف
Shabana,Ayah Mohammed Zaki
هيئة الاعداد
باحث / Ayah Mohammed Zaki Shabana
مشرف / Safaa Shafik Imam
مشرف / Ghada Abdel Wahed Ismail
مشرف / Ola Galal Badr El-Deen
الموضوع
Infection and Antimicrobial Selection Patterns-
تاريخ النشر
2013
عدد الصفحات
189.p:
اللغة
الإنجليزية
الدرجة
ماجستير
التخصص
طب الأطفال ، الفترة المحيطة بالولادة وصحة الطفل
تاريخ الإجازة
1/1/2013
مكان الإجازة
جامعة عين شمس - كلية الطب - Pediatrics
الفهرس
Only 14 pages are availabe for public view

from 189

from 189

Abstract

The present retrospective study was conducted in Ain Shams University Children’s Hospital NICU using the records of the year 2011. The recorded data included: gestational age, birth weight, gender, mode of delivery, age and diagnosis at admission, order of birth, referral data, relevant perinatal history such as PROM, laboratory results of CRP, TLC, and cultures on admission and subsequently done cultures, duration of hospital stay and outcome. Interventions with risk for sepsis were recorded together with the resistance/sensitivity patterns of the prevalent organisms in comparison to the prescribed antibiotics.
They were 145 neonates; 78% full-term and only 6% were <32 weeks’ gestation; 77 males and 68 females; 93 were presenting for the first time and 52 were referred from other NICUs. The patients were categorized into sepsis (n=69) and no-sepsis (n=76) groups on basis of clinical and laboratory criteria. Sepsis group were subsequently subdivided into early-onset, late-onset and nosocomial sepsis subgroups (each was 30% of total sepsis patients).
The overall incidence of sepsis was 47.6%, with a nosocomial sepsis rate of 14.9/1000 patient days. The mortality rate was 32.6%; most of them (87%) were septic patients. The overall case fatality for invasive bacterial infection was 59%, and was highest among neonates with LOS (66.7%).