الفهرس 
Anatomy of the ocular surfaceOnly 14 pages are availabe for public view
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Abstract
An essential perquisite for clear good vision is to have a smooth
corneal surface epithelium supporting an intact tear film. Physiologically,
a natural turnover of corneal epithelial cells occurs in which superficial
cells shed from the epithelial surface and replaced by those from
underneath. In turn, basal epithelial cells migrate inward from the
periphery, replenishing the population of the deeper corneal epithelial
cells. The source for new cells to keep the integrity of this system is
believed to be the corneal epithelial stem cells, which are strongly
thought to reside mostly in the palisades of Vogt in the limbal region.
The SC niche hypothesis model proposed by Schofield in 1983,
suggests the importance of intrinsic properties (characteristics inherent to
the cell) and extrinsic properties (characteristics of the SC environment)
in maintaining “stemness.” The limbus and particularly the palisades of
Vogt are thought to contain the CESC niche. If the palisades of Vogt at
the limbus represent the LSC niche, then the basement membrane and
stromal matrix in this zone must be different from that seen in the central
cornea to allow the “stemness” of these cells to be maintained. Indeed,
the limbal epithelium of the palisades of Vogt has many differences
(characteristics) from the central corneal epithelium.
Key Words :
· Autologous Serum – Cytokeratins - Dalton