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العنوان
Bacterial Infections Associated with Orthopedic Implants /
المؤلف
Aly, Reham Aly Ibrahem.
هيئة الاعداد
باحث / Reham Aly Ibrahem Aly
مشرف / Gamal Fadl Mahmoud Gad
مشرف / Adel Anwar Abd El-Aziz
الموضوع
Bacterial diseases - Epidemiology. Bacterial diseases - Prevention. Bacterial Infections - Epidemiology. Bacterial Infections - prevention & control.
تاريخ النشر
2013.
عدد الصفحات
222 p. :
اللغة
الإنجليزية
الدرجة
الدكتوراه
التخصص
الصيدلة ، علم السموم والصيدلانيات (المتنوعة)
تاريخ الإجازة
1/1/2013
مكان الإجازة
جامعة المنيا - كلية الصيدلة - Microbiology
الفهرس
Only 14 pages are availabe for public view

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from 212

Abstract

Infection is a common, serious complication related to insertion of fracture-fixation devices or prostheses. Although potenti~lly beneficial, the administrations of systemic antimicrobial prophylaxis and compliance with the usual measures to control infection have not completely eradicated infections associated with the use of these devices. An
infection a~30ciated with a fracture-fixation device is generally difficult to eradicate without removal of the device and is expensiv(~ to treat due to produce an extracellular polysaccharide matrix (biofilm).
This study was performed to demonstrate the incidence of orthopedic implants acquired infections inpatients in the department of orthopedics at Minia university hospital, resistance of isolated microorganisms to different antibiotics, their ability to form biofilm in vitro, degree of bacterial adhesion to certain biomaterials used in orthopedic surgery and the effect of gentamicin, sodium. salicylate each alone and in combinations on the bacterial adherence.
A total of 89 bacterial isolates were recovered frGm 83 patients with orthopedic implants (9 prostheses, 36 plates, pins and screws, 181M nails and 20 Illiazarov wires). 67 (80.70/0) Patients had a positive culture,
while in 16 (19.30/0) patients, the culture was negative.
It was found that 37.30/0 of samples represent mixed bacterial infections while, 62.7% of samples :epresent single bacteri.al isolate.