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العنوان
Study of the potential effect of selenium
on gamma-radiation induced ovarian failure\
الناشر
Ain Shams university.
المؤلف
Said ,Riham Soliman Mabrouk.
هيئة الاعداد
مشرف / Ahmed Shafik Nada
مشرف / Ebtehal El-Demerdash Zaki
مشرف / Ahmed Shafik Nada
باحث / Riham Soliman Mabrouk Said
الموضوع
gamma-radiation. Selenium. ovarian failure.
تاريخ النشر
2012
عدد الصفحات
p.:226
اللغة
الإنجليزية
الدرجة
ماجستير
التخصص
العلوم الصيدلية
تاريخ الإجازة
1/1/2012
مكان الإجازة
جامعة عين شمس - كلية الصيدلة - Pharmacology and Toxicology
الفهرس
Only 14 pages are availabe for public view

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Abstract

The present study was designed to examine whether Se in the form of sodium selenite has any significant role on ϒ-radiation induced ovarian-uterine dysfunction in vivo by studying its effects on different markers of oxidative stress, apoptosis, proliferation and folliculogenesis in an experimental model of ϒ-radiation induced ovarian failure in rats. The study was designed as follows: Animals were divided randomly into four groups and were either exposed to a single dose of ϒ-radiation (3.2 Gy) and/or treated with sodium selenite (0.5 mg/kg, once daily for one week).