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العنوان
Phenotypic and Genotypic characterization of Salmonalla Typhi Clinical Isoiates /
المؤلف
Hussin, Farid Ali Abd Aliem.
هيئة الاعداد
باحث / Farid Ali Abd AL Aliem Hussin
مشرف / Ahmed Ahmed Abd El-Aziz
مشرف / Tarek El-Said El-Banna
مشرف / Fatma Ibrahim Sonbol
الموضوع
Pharmaceutical Microbiology.
تاريخ النشر
2013.
عدد الصفحات
p 171. :
اللغة
الإنجليزية
الدرجة
ماجستير
التخصص
العلوم الصيدلية
تاريخ الإجازة
13/8/2013
مكان الإجازة
جامعة طنطا - كلية الصيدلة - Pharmaceutical Microbiology
الفهرس
Only 14 pages are availabe for public view

from 202

from 202

Abstract

In vitro,as well as in vivo antimicrobial agent(AMA)resistance in typhoid fever for drug of choice(DOC) e.g.cidocetin(chloramphenicol 82.9% )&septazole(co trimoxazole 8.6%) the main drugs to be used in tropical hospitals&may became the sole regime in the treatment of such cases in the Governmental Hospitals & in private sector.Therefore,the treatment pattern failure becomes general problem in the management of typhoid fever.Resistance to antimicrobial agents,mediated by various mechanisms,plays an important role in the failure of antimicrobial agent-based treatment of various infectious diseases.As a result,these diseases re-emerge rapidly hence the endemicity Antimicrobial agents therapy may be altered accordingly, this resistance may be tailored by using new groups of AMAs for e.g. third generation cephalosporins (CTX 11.4%,CEP 5.7%,CRO 2.9%) and /or quinolones (CIP,NOR 0% and NA 2.95%) According S.typhi and S.paratyphi resistance profile the least effective AMA was C followed by Amp and there resistance ratio were 86% & 82 % respectively. The most potent AMAs in this study were 100% active CIP, NOR,GN and surprising TE.Some AMA patterns repeated with many isolates such as (AMP- C)which posses resistance to 17(48.6%) also (AMP-AMC-C)that repeated with 6(17.1%).While (AMP-C-FOX) in 5(14.3%) and (AMP- C-AMC-S) in 2 (5.7%).