الفهرس 
Endothelial function Normal Endothelial FunctionOnly 14 pages are availabe for public view
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Abstract
This study included 95 patients who were attending at the cardiology department at Fayoum university hospital. Those patients were classified into two groups: Group I; Ischemic heart disease (patients with coronary insufficiency evidenced by symptoms of IHD, ECG and echocardiographic evidence of segmental variations in wall motion & coronary angiography) including 63 patients and Group II; control subjects with normal coronary angiography (number=32)
History taking, clinical examination, 12-lead ECG, routine laboratory testing, echocardiographic study, Carotid arterial duplex, coronary angiography and analysis of the endothelial NOS3 gene polymorphism were subjected to detection of Glu298→ Asp Endothelial Nitric Oxide Synthase gene polymorphism using PCR-RFLP.
The study concluded that the heterozygous and homozygous Asp mutants of the endothelial nitric oxide synthase enzyme gene polymorphism were not associated with occurrence of coronary artery disease or increased carotid intima media thickness in studied population.