الفهرس 
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Abstract
This study included fifty patients with chronic hepatitis C related cirrhosis and fourty three healthy controls. Full history taking and complete clinical examination were done for every case. As regards laboratory part of the work the following
laboratory investigations were carried out: complete blood count (CBC), liver profile (serum albumin, serum bilirubin, ALT, AST and Alkaline phosphatase), HBs Ag and HCV Ab and blood sugar (FBS, 2hr pp). Also abdominal Ultrasono-graphy was done. The immunological part of the work was the estimation of the antibody
titre for cytomegalovirus both (IgG) and (IgM) by ELISA.
The results of clinical examination revealed hepatomegally in 41 cases (82%), splenomegally in 46 cases (92%), ascitis in 46 cases (92%), lower limb oedema in 29 cases (58%), haematemesis
in 5 cases (10%), fever in 21 cases (42%) and there is no case had lymph node enlargement.
Estimation of antibody for cytomegalovirus IgM was negative in 34 cases (68%) and positive in 16 cases of CMV IgM (32%). As regard of CMV IgG titre was negative in 17 cases (34%)
and positive in 33 cases (66%).
There was a higher mean CMV IgM among cases 1.42 compared to 0.4 among controls and the difference is highly significant statisatically.
There was no statistically significant difference between the two groups as regards the mean CMV IgG.
There was a lower mean hemoglobin, lower mean RBCs,hematocrite, MCH, MCHC, platelets count among cases compared to controls and the difference is highly significant statistically.
There was no significant difference statistically between cases and controls as regards the mean WBCs.
There was a lower mean neutrophil among cases compared to controls and the difference is highly significant statistically.
There was a higher mean lymphocytic count among cases compared to controls and the difference is highly significant statistically.
There was a higher mean serum bilirubin, ALT, AST among cases compared to controls and the difference is highly significant statistically.