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العنوان
Biochemical assessment of silver nanoparticles on erlich ascites carcinoma in an experimental animal /
المؤلف
Darwish, Mohmoud Ibrahiem Mohie EL-Din.
هيئة الاعداد
باحث / Mohmoud Ibrahiem Mohie EL-Din Darwish
مشرف / Sydat Saad AbdEL-Magid
مشرف / Medhat Mohamed Fawzy
مشرف / Hussein I. El-Belbasi
الموضوع
Laboratory animals. Veterinary Biochemistry.
تاريخ النشر
2013.
عدد الصفحات
149 p. :
اللغة
الإنجليزية
الدرجة
ماجستير
التخصص
البيطري
تاريخ الإجازة
1/1/2013
مكان الإجازة
جامعة الزقازيق - كلية الطب البيطرى - department of Biochemistry
الفهرس
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Abstract

Cancer is considered one of the most common causes of mortality worldwide. The target of much research has been on
the discovery of natural and synthetic compounds that can be used in the prevention and/or treatment of cancer, in this research we focused on silver nanoparticles as anti -cancer
agents.
The application of silver nanoparticles as anticancer agent was done through using 54 female swiss albino mice which
divided into 5 different groups as following:
Group I (negative control group) Group 2 (positive control group): induction of tumor (was inoculated with 2.5 x106 EAC cells Lp) and no treatment with silver nanoparticles.
(Treated groups): induction of tumor (was inoculated with 2.5 xl06 EAC cells Lp) and treated with AgNPs and this group divided into 3 subgroups according to the dose of treatment:
The first dose 3.91ul of nanosilver solution daily i.p for
each mice. (group3).
The second dose 7.83ul of nanosilver solution daily i.p for
each mice. (group4).
The third dose 15.66 ul of nanosilver solution daily i.p for
each mice. (group5).
After 5 and 10 days from injection of nanosilver the
animals were sacrificed. Blood samples were taken for
separation of serum an measurment of tumor markers (CEA and
CAts.3). Ascetic fluid samples were taken for doing viability test