الفهرس 
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Abstract
In vitro antibacterial effect
Antibacterial effects of colistin (10 ug) flumequine (30 ug) and their combination were studied in vitro using disc diffusion method against S. pullorum and E. coli. The degree of sensitivity was determined by measuring the diameter of the inhibition zones . The sensitivity of E. coli and S. pullorum to commercial discs of antibiotics namely flumequine, colistin, nalidixic acid, gentamycin,
chloramphenicol, erythromycin and streptomycin was also determined
k’lcompare the efficacy of the tested drugs with the other antibiotics.
Flumequine was the most powerful antimicrobial agent against
coli (24 mm) where as chloramphenicol (22mm) was the most ective drug against S. pullorum followed by flumequine (21.7mm) . list in was less potent than flumequine against S. pullorum (11 mm)
The combination of colistin flumequine proved to be the most
ent antibacterial against S. pullorum (24 mm) and E. coli (26 mm) .
vivo antibacterial effects :
Colistin flumequine combination was studied against S. pullorum
E. coli in vaccinated chicks with New castle and Gomboro
cines. The combination was tested against infected and non