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العنوان
Multi-detector Computerized Tomography in pre-operative evaluation of living donors for liver transplantation/
المؤلف
Sliem ,Yousef Ahmed Yousef ,
هيئة الاعداد
باحث / يوسف أحمد يوسف سليم
مشرف / فردوس عبد الرؤوف عابدين
مشرف / أحمد مصطفى محمد
الموضوع
Multi-detector Computerized Tomography<br> liver transplantation
تاريخ النشر
2010
عدد الصفحات
136.p:
اللغة
الإنجليزية
الدرجة
الدكتوراه
التخصص
الأشعة والطب النووي والتصوير
تاريخ الإجازة
1/1/2010
مكان الإجازة
جامعة عين شمس - كلية الطب - Radiodiagnosis
الفهرس
Only 14 pages are availabe for public view

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from 136

Abstract

Liver transplantation is a successful treatment option, with its capacity for increasing the one year-life expectancy in chronic liver disease and liver failure. One of the most important problems experienced in liver transplantation is the rapid increase in the difference between the number of patients in need for liver transplantation and the number of available cadaver livers. For that reason, liver transplantation from a living donor has been introduced as an alternative to liver transplantation from cadavers. Liver transplantation from a living donor has some advantages such as the increased number of organs available for transplantation, chance of performing the operation in elective conditions, and elimination of the waiting period for the recipient for a cadaver organ. These factors decrease morbidity, mortality and cost. Shortened period of cold ischemia and obtaining the liver from a living donor are the other advantages. Right lobe liver transplantation is performed in adults, as opposed to pediatric population, since left lobe lateral segment graft fails to meet the metabolic needs of the adult recipient.
The main purpose of pre-operative imaging in liver transplantation is to expose the arterial and venous vascular map. It is necessary to image the vascular structures properly prior to transplantation due to the complex nature of liver vascular anatomy and its frequent variations. CT is a useful method not only in the determination of hepatic arterial anatomy, the source of the segment IV artery, hepatic venous anatomy, accessory hepatic veins and portal vein variations, but also in the evaluation of bile ducts, liver volume and steatosis in the potential donor.
The multislice (multidetector) CT angiography technique, which has been spreading widely for the last years, is a method that allows faster volume imaging of the whole liver with thinner slices in high spatial resolution within one breath-hold period, when compared with the CT devices with a single detector row. The isotropic two- and three dimensional images, which were obtained by using thin slices rendered possible CT angiography of the relatively thinner vascular structures.
MSCT angiography provides comprehensive and accurate preoperative information of potential donors for LRLT. This information has a major impact on donor selection and allows better planning of a safer surgical approach, which can be expected to reduce postoperative complications. MSCT angiography is a non-invasive and reliable method in evaluating hepatic vascular anatomy in potential LRLT donors. Therefore, MSCT angiography is recommended as a routine preoperative examination for potential LRLT donors. The introduction of 64, 128 and especially 320-detector row spiral CT machines allow a lower pitch and faster speed through thinner slices.