الفهرس 
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Abstract
The present work was aimed to assess the use of C. papaya seeds to control the early breeding in O. niloticus, which often result in low marketable-sized fish and overpopulation in production system with young (stunted) fish, as well as to determine its effects on growth performance, biochemical, physiological and histo-pathological aspects of tilapia fish.
This study was carried out at the aquaculture laboratory in the Department of Marine Science, Faculty of Science, Suez Canal University, Ismailia, Egypt, during the period between 15th of April and the end of July 2012. A total of 150 apparently healthy fish with an average initial weight of 30±1 g were used in this experiment. The mixed six fish were obtained from Fish Research Center, Faculty of Agriculture, Suez Canal University, Ismailia, Egypt, while monosex fish obtained from Egyptian Company for Fisheries, El-Abbassa, Abou Hamad, El-Sharkia, Egypt. C. papaya fruits were cut open to remove their seeds which shade dried, milled into fine particle size (<250 μm) and kept in a dry clean air-tight plastic container.
Fish were leaved without feeding during the first day, then adapted gradually to the experimental diets and aquarium conditions in the laboratory for two weeks of acclimatization. Fish distributed equally (10 fish/aquarium) in 15 glass aquaria (135×50×60 cm), with temperature maintained at 30±1 ºC. Five experimental triplicate groups were prepared; G1 was mixed sex fish fed on basal diet (negative control group), G2 was monosex fish fed on basal diet (positive control group), G3 was mixed sex fish fed on basal diet with adding 60 g of C. papaya seeds/kg (low dose treatment), G4 was mixed sex fish fed on basal diet with adding 90 g of C. papaya seeds/kg (medium dose treatment) and G5 was mixed sex fish fed on basal diet with adding 120 g of C. papaya seeds/kg (high dose treatment).