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العنوان
Morphological Changes ofGastrointestinal Mucosa in Cases of Portal Hypertension/
المؤلف
Osman,Mohammed Abobakr,
هيئة الاعداد
باحث / محمد أبوبكر عثمان
مشرف / توفيق سعد محمد فهيم
مشرف / نجلاء مدحت ابراهيم ابو رابيه
مشرف / هشام محمد عمران
الموضوع
Morphological Changes ofGastrointestinal Mucosa<br>Portal Hypertension
تاريخ النشر
2013
عدد الصفحات
168.p:
اللغة
الإنجليزية
الدرجة
ماجستير
التخصص
طب العيون
تاريخ الإجازة
1/2/2014
مكان الإجازة
جامعة عين شمس - كلية الطب - General Surgery
الفهرس
Only 14 pages are availabe for public view

from 166

from 166

Abstract

Awareness of the association between portal hypertension and changes in the gastric microcirculation has increased, so portal hypertensive gastropathy has emerged as a distinct entity. Several controversies exist on the endoscopic appearance, the histological findings and clinical significance of portal hypertensive gastropathy. The mucosal and vascular changes of the stomach in patients with portal hypertension may be a manifestation of splanchnic dilatation and gut hyperemia found in those patients.
This work aimed to assess the changes of the gastric mucosa in patients with portal hypertension as regard to the endoscopic appearance and histological findings of PHG.
Portal hypertensive gastropathy was encountered in(32.5%) patients after thorough endoscopic examinations, among them (30%) cases had mild form of portal hypertensive gastropathy and only (2.5%) case with severe form.
As regard the location and distribution of portal hypertensive gastropathy, the fundus was affected in (69.2%) of cases, while the body was affected in (52.8%) of cases and the antrum in (30.7%) of cases.
Endoscopic mucosal biopsy revealed mucosal ectasia in of 50% cases, while cellular infiltration was recorded in 35% of cases.
Ectasia was present in 84.6% of cases with endoscopic gastropathy and in 33.3% in cases without gastropathy, while cellular infiltration was present in 38.4% in patients with endoscopic gastropathy and m 33.3% in patients without gastropathy.