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Abstract Laparoscopic cholecystectomy (LC) is the gold standard for the surgical treatment of symptomatic gallstones. The advantages of this surgical approach have included a positive impact on the postoperative quality of the patient’s life as well as optimal short- and long-term results Alternative techniques for cystic duct closure have included sutures, a three-throw reef knot, or Roeder slip knots. However, these alternatives are technically more difficult and, therefore, were used infrequently Ultrasonically activated scissors may divide both vessel and cystic duct, with no need of further ligature, and possibly reduce the risk of thermal injuries Designed as a safe alternative to electrocautery for the hemostatic dissection of tissue, the ultrasonically, activated (Harmonic) scalpel was introduced into clinical use nearly a decade ago It was hypothesized that use of the harmonic scalpel for dissection of the gallbladder would lessen the frequency of perforation in comparison with electrocautery, and turn would improve the operative course of laparoscopic cholecystectomy Ultrasonic dissection produces a smaller zone of tissue damage and less loss of nerve function, and has been suggested as an alternative to electrocautery, it has been associated with a shorter operating time, reduced hospital stay less blood loss compared with electrocautery dissection in a randomized study of laparoscopic cholecystectomy. |