Search In this Thesis
   Search In this Thesis  
العنوان
Value of Assessment of VANIN-1 in Patients with Immune Thrombocytopenic Purpura (ITP/
المؤلف
Mohammed,Inas Abdel Moaty
هيئة الاعداد
باحث / إيناس عبد المعطي محمد
مشرف / عبد الرحمن عبد الحميد سليمان
مشرف / هاني محمد عبد الله حجاب
مشرف / ولاء على السلكاوى
الموضوع
Thrombocytopenic Purpura (ITP)
تاريخ النشر
2014
عدد الصفحات
167.P:
اللغة
الإنجليزية
الدرجة
ماجستير
التخصص
الطب الباطني
تاريخ الإجازة
12/3/2014
مكان الإجازة
جامعة عين شمس - كلية الطب - Internal Medicine and Clinical Hematology
الفهرس
Only 14 pages are availabe for public view

from 157

from 157

Abstract

O
ur findings suggest that vanin-1 may contribute to the pathogenesis of ITP, indicating that vanin-1 is an important target for further investigation.
Vanin-1 is a potentially important molecule that acts as an oxidative stress response gene that is leads to creation of new therapeutic approaches and medications.
Vanin-1 may be used as blood marker that can distinguish ITP from other causes of thrombocytopenia as healthy individual has low expression of vanin-1
Large cohorts in healthy controls, adult patients with ITP, and possibly in pediatric patients with ITP as well as in patients with thrombocytopenia from other causes will demonstrate the clinical benefit of Vanin-1.
Such studies will advance understanding of ITP pathophysiology and will clarify the role of vanin-1 in risk stratifying patients, which is especially important in light of the introduction of new therapeutic agents.