الفهرس 
IntroductionOnly 14 pages are availabe for public view
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Abstract
Hyperbaric oxygen therapy is defined by the Undersea and Hyperbaric Medical Society as a treatment in which a patient intermittently breathes 100% oxygen while the treatment chamber is pressurized to a pressure greater than sea level. The pressure increase must be systemic.
Our aim of this review is to high-light the role of hyperbaric oxygen therapy in management of different pediatric neurological disorders.
Hyperbaric oxygen acts in CP by the delivery of 100% oxygen under pressure, which helps in reactivation of sleeping brain cells that can be found surrounding injured areas in the brains of children with CP. It is also believed that hyperbaric oxygen therapy reduces swelling in the brain by constricting blood vessels, and “provides an ideal internal environment for the growth of new brain tissue”.
As a treatment for autism, HBOT helps overcome hypoperfusion, has potent anti-inflammatory effects and reduces oxidative stress.
Hyperbaric oxygen therapy is a further adjunctive therapy that has been proposed to improve outcomes in acute brain injury.
Hyperbaric oxygen therapy was first reported to improve the outcome following acute noise-induced hearing loss, sudden deafness, and peripheral vestibular disorders, during the late 1960s by both French and German authors.
Complications with HBOT are related to the toxic effects of oxygen, including myopia, cataracts, barotraumas, decompression sickness, oxidative stress associated with lipid peroxidation as well as the generation of ROS, oxygen-induced seizures, and pulmonary oxygen toxicity.
In human medicine, pneumothorax is the only absolute contraindication for HBOT. Relative contraindications include emphysema with bulla formation, asymptomatic pulmonary lesions, history of thoracic or ear surgery, uncontrolled high fever, pregnancy, claustrophobia, and upper respiratory infection.
Conclusion
Hyperbaric Oxygen Therapy is still not yet evidence based in treatment of neurological disorders, but may be useful as an adjuvant therapy in many neurological disorders such as autism, cerebral palsy, idiopathic sudden sensorineural hearing loss, and traumatic brain injury.