الفهرس 
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Abstract
Summary and conclusions
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Depending on the results of the present study it could be concluded that:
1. Clonidine resulted in a general reduction in locomotor and exploratory activity.
2. Clonidine induced depression associated with increase in aggressive behavior.
3. Imipramine at the selected dose did not change aggressive behavior induced by clonidine.
4. EGCG significantly reduced immobility in the FST but did not alter locomotor activity in the open field test at low dose, suggesting that GTP has antidepressant-like effects, and this action did not induce nonspecific motor changes.
5. Treatment with EGCG in a dose of 25 and 50mg/kg to depressed rats may show antidepressant action through affecting neurotransmitter systems as it significantly increased brain neurotransmitters.
6. EGCG has a promising antidepressant-like effect through its anti-inflammatory activity, as it decreased COX-2 expression.
7. EGCG (50mg/Kg) may reduce aggressive behavior in depressed rats.
8. Finally, it could be concluded that EGCG may has a promising antidepressant-like effect through its effect on neurotransmitters level and anti-inflammatory activity, where it managed to increase curiosity, self-interest, the will to live, increased swimming in FST, decreased COX-2 expression and all those effects are dose related.