الفهرس 
Systemic Lupus Erythrematosus (SLE)Only 14 pages are availabe for public view
 |  | from | 177 |  |  |
| | | from | 177 | | |
Abstract
This study aimed to : Systemic lupus Erythematosus (SLE) is a multisystem, autoimmune, connective-tissue disorder with a broad range of clinical presentations. Due to the extreme heterogeneity of the diseasethere are currently a very limited number of consensus biomarkers to aid the treatment decision-making in SLE. Aim of the work: Detection of the levels of both urinary and serum NGAL in SLE patients either suffering from lupus nephritis or not and to correlate both urinary and serum NGAL with scores of disease activity and severity. Conclusion: Neutrophil gelatinase-B associated lipocalin (NGAL)/Lipocalin-2 has been implicated in the pathogenesis of several disease states in different organ systems, and especially in kidney diseases. Clinically, urinary NGAL significantly correlates with measures of lupus nephritis disease activity and can be a powerful marker for lupus nephritis.