الفهرس 
INTRODUCTIONOnly 14 pages are availabe for public view
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Abstract
One hundred and twenty adult male albino rats were used in this study. Animal’s weighting120 ± 10g were divided randomly into equal six groups (20 rats for each group) as follow: the first group of rats were served as a control. The animals of the second group were administrated by ciprofloxacin7.2 mg / rat for 14 consecutive days. Animals of the third group were exposed to a single dose of γ- irradiation (1Gy) .The fourth group were exposed to a single dose of γ- irradiation (5Gy) .The animals of fifth group were exposed to a single dose of γ- irradiation (1Gy),after 24hrs rats were administrated by ciprofloxacin7.2 mg / rat for 14 consecutive days. Animals of sixth group were exposed to a single dose of γ- irradiation (5Gy), after 24hrs rats were administrated by ciprofloxacin7.2 mg / rat for 14 consecutive days. Blood sampling were collected from ten rats of each group after one week while the other ten rats after two weeks. The following parameters were estimated for each rat after one and two weeks: blood hemoglobin (Hb) and white blood cell count (WBCs), serum levels of urea, creatinine, albumin, alkaline phosphatase(ALP), alanine amino transferase (ALT), aspartate amino transferase (AST), copper ions (Cu+2) , iron ions (Fe+3), total iron, ceruloplasmin ,total iron binding capacity , ferritin, transferrin, and glutathione peroxidase (GPx).The following results were compromised with their corresponding control groups: blood hemoglobin recorded a significant decrease in groups of rats administrated by ciprofloxacin , group of rats exposed to (1Gyor5Gy) γ-irradiation and group of rats administrated by ciprofloxacin post-irradiation (1Gyor5Gy) after one week of the experiment.