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Abstract The meniscus plays an important role in protecting the health of the knee joint. Once the meniscus has been torn and is removed from the joint, options are limited to replace this tissue. Meniscal allograft transplantation is a viable option showing increasing evidence of clinical utility, although the high cost, limited availability, and risk of disease transmission from allografts may preclude their widespread use. Another option such as the collagen meniscus implant (CMI) is under investigation as a potential partial meniscal replacement. In the future, stem cells may provide an alternative, potentially autogenous, source of meniscal tissue to regenerate the resected segment. Even with these advances, however, surgeons should continue to attempt meniscal repair whenever feasible and resect as little meniscal tissue as possible in tears that are deemed irreparable. |