الفهرس | Only 14 pages are availabe for public view |
Abstract Portal hypertension is a common clinical syndrome defined hemodynamically by pathologically elevated portal pressure. The most common cause of portal hypertension is liver cirrhosis. In patients with liver cirrhosis and portal hypertension, gasteroesophageal varices and portal hypertensive gastropathy are well described. These complications are the most common causes of upper gastrointestinal bleeding in these patients. However, only few reports have investigated the duodenal lesions in patients with portal hypertension in detail. Data about the effect of esophageal variceal eradication by band ligation on the presence and severity of portal hypertensive duodenopathy is still conflicting. The aim of our study was to evaluate the duodenal mucosal changes endoscopically and histopathologically in patients with liver cirrhosis and portal hypertension before and after esophageal variceal eradication by band ligation, and their relation to immunohistochemical study of vascular endothelial growth factor (VEGF) tissue expression. |