الفهرس | Only 14 pages are availabe for public view |
Abstract The management of chronic venous leg ulcers poses a great challenge because of their high prevalence, refractory nature and their economic consequences on the health care system. Autologous skin graft, which is the current treatment of choice, creates a wound at the donor site. Although bioengineered skin substitutes are available, they are too expensive for the routine clinical use. The amniotic membrane (AM) drew our interest because of its successful use in ophthalmology since long time and because of its properties of promoting epithelialization and granulation, infection controlling and pain reducing. Furthermore, it is cheap, easily available, and easy to preserve and apply. The aim of this study was to evaluate the efficacy and safety of amniotic membrane dressing in treatment of chronic venous ulcer of the lower limb.This prospective and comparative study was conducted at the vascular surgery unit, general surgery department, Tanta University from February 2013 to December 2013.We studied 45 patient (bilateral ulcers in 5 patients). Limbs were equally & randomly divided into 25 ulcers in group A (which underwent the AM dressing) and 25 ulcers in group B (which underwent the saline dressing). (In patients with bilateral ulcers one limb was taken as test and the other as control). |