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Abstract Morbidity and mortality from asthma have increased over the past decade despite improved understanding and significant advances in medical therapeutics (Janice et al., 1992). This increase in morbidity and mortility from asthma increases the benifit of pragmatic trials in bronchial asthma. The aim of pragmatic trials is to determine the place of a drug in the management of a disease and improve medical decision making (Lurie et al., 1991). The goals of the long term management of asthma is to find the minimum treatment that control symptoms allow resumption of normal life, prevent severe attack and death and control airflow obstruction (Lurie et al., 1991). |