الفهرس 
Introduction and aim of the work
Aim of the workOnly 14 pages are availabe for public view
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Abstract
Tissue Doppler Imaging (TDI) is a rapid, inexpensive and noninvasive method for theassessment of both systolic and diastolic cardiac function and it has proved to be a useful prognostic tool both in the general population and among persons with known cardiovascular disease.TDI visualizes myocardial velocities by measuring low frequency, high-amplitude signals of myocardial motion.
This study was performed to determine how the left ventricular wall motion assessed by echocardiographic Tissue Doppler Imaging (TDI) is affected by increasing severity of coronary artery disease (CAD) among patients with stable angina pectoris and preserved ejection fraction.
This study included 55 patients with chronic stable angina, who were referred to Assuit University Hospital cath lab to do coronary angiography. They were divided into two groups the group I with non-significant coronary stenosis (25) and the group II with significant coronary stenosis (30). The latter had been further subdivided into 3 sub- groups each of 10 patients (patients with single vessel, double vessel and multivessel). They were also referred to echocardiographic unit where conventional echocardiography and TDI were performed.
This study found that Global systolic performance by TDI (in terms of global sʹ) was negatively correlated to the number of vessels with significant stenosis. In one- and two-vessel disease, eʹ decreased significantly (p-value 0.034 and 0.006 respectively). In patients with one-vessel disease, aʹ increased compensatory with a significant reduction of eʹ/aʹ-ratio (p-value 0.002).
This study reached to a conclusion that TDI performed at rest reveals both diastolic and systolic dysfunction in patients with stable angina pectoris even when the ejection fraction is preserved and the nature of the cardiac dysfunction
depends on the severity of the CAD.
Recommindations from the present study:
To use TDI as a diagnostic as well as aprognostic tool in patients with chronic stable angina even with normal EF.