الفهرس 
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Abstract
The liver plays a major role in regulating various physiochemical functions of the body, including synthesis, secretion and metabolism of xenobiotics. Damage to the hepatic parenchyma will lead to deleterious effect on liver physiochemical functions. Many factors may induce such damage, including infectious agents and hepatotoxic chemicals. The present study aims to investigate the hepatoprotective effects of Tempol, against CCl4 induced oxidative stress and liver injury. These results declared that Tempol has an anti-inflammatory as well as antioxidante action through inhibiting the synthesis of TNF-α, where Tempol pre-treated mice showed a much lower expression level of TNF-α compared to its expression level in the mice of CCL4-treated group. In the same time, it was able to keep the level of GSH in the Tempol pre-treated group higher than its level in CCL4 group.