الفهرس 
Introduction
Airway inflammation in asthmaOnly 14 pages are availabe for public view
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Abstract
This observational study of induced sputum in asthmatic patients receiving different forms of treatment provided us with the opportunity to compare sputum cell indices in asthmatic patients under different forms of treatment and others not treated which revealed that patients without treatment were not controlled and patients on treatment vary in the degree of control according to proper treatment. Also showed different inflammatory subtypes of asthmatic patients. Induced sputum examination for inflammatory markers holds much promise in the evaluation of the anti-inflammatory properties of asthma medications and identifying the appropriate medication to control symptoms. They may be useful to compare the relative potencies of different anti-inflammatory drugs.
Our study showed reduction in eosinophils % of asthmatic patients receiving ICS compared to other patients were not treated which is significant, and also, showed that patients with asthma control (n=16), in which, ten of them show eosinophilic inflammation and six (two are controlled and four are uncontrolled) show neutrophilic inflammation, however no significant difference was found between the 2 groups (p-value >0.05). So we can use the induced sputum eosinophil count to titrate treatment results which may help in lowering the exacerbation rate with no overall increase in medication.
The majority of international asthma guidelines have not yet unequivocally endorsed the use of induced sputum as noninvasive measurements of airway inflammation in the diagnosis and management of asthma. Induced sputum analysis is recommended for every patient diagnosed as bronchial asthma before starting asthma management and for asthmatic patients who are not controlled on full asthma management to understand type of airway inflammation in all guidelines.