الفهرس | Only 14 pages are availabe for public view |
Abstract Acquired immunodeficiency syndrome (AIDS) is one of the most important problems for medical practitioners. This syndrome was first recognized in 1981, (C.D.C. 1981), and reported 1983, (Barre-Sinoussi et al a retrovirus called human (HIV) (Levy, et al, 1984), as a viral disease in 1983). It is caused by immunodeficiency virus which infects T helper lymphocytes, causing T dysfunction and depletion resulting in opportunistic infections, Kaposi sarcoma and other neoplasm (Gallo, et al, 1982). Primary methods of transmission are by sexual contact, blood products, intravenous inoculations with contaminated needles or in utero infection, homosexual men, intravenous drug users and hemophiliacs being the classic risk group (Curran, 1985). It is possible that patients undergoing hemodialysis treatment, who need multiple transfusions for anemia or preparation for renal transplantation, run a higher risk of acquiring the infection (Peterman, et al, 1986). However there is no evidence to date that- 2 - AID has been contracted by a patient during HD, which could depend on the low infectivity and lability of HIV (Poole, et al, 1985). Renal transplantation from infected donors could be another vehicle of transmission. the prevalence of human immunodeficiency virus (HIV) among patients undergoing maintenance hemodialysis varies in different geographic areas (Morrison, et al, 1986). Screening for antibody to HTLV-111/LAV in dialysis centres is important as a help in prevention of infection (Peterman et al, 1986). So to obtain more precise information on the prevalence of acquired immunodeficiency syndrome in patients undergoing hemodialysis. We have conducted a controlled serological and clinical study involving a reasonable number of patients .. Aim of the Work: Study the prevalance of HTLV-III infection in patients with chronic renal failure under regular hemodialysis. |