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Abstract Genetic factors have become incredslngly 1mport ant causes for both congenital and acquired eye disease 1n the pediatric age group. accurate statistics are not available. timated that at least 50% of new cases Although 1t lS esot .!~9_ct_I blindness ln the pediatric age group can be attributed to genetic causes. The heredity bases of diseases that affect the eye Include all three broad categories: chromosomal aberration. s1ngle gene mutations consis tent with Mendelian inheritance patterns, and multifactorial Inheritance; monogenic disorders can be divided into those that only affect the eye and ocular adnexae, and those that are mult1system. Geneocopies. similar physical character1st1cs caused by different genetic mechanisms, complicate the evaluation of many genet1c d1sorders of the eye, including microphthalmia and retin1t1s pigmento::sa (84t61Jttn~ 1.98.3). AIM OF WORK ThiS study lS made to show the role of genetics (and cytogenetics) 1n the d1agnosis dnd classlflcation of ocular congenital d1sorders. |