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العنوان
genetic study on common congenital ocular disorders/
المؤلف
OMAR, SAHAR ABDEL KHALIK
هيئة الاعداد
باحث / SAHAR ABDEL KHALIK OMAR
مشرف / ABDEL KHALIK KHATTAB
مشرف / MOHAMED AWADALLA
الموضوع
HUMAN GENETIC.
تاريخ النشر
1990.
عدد الصفحات
335p;
الفهرس
Only 14 pages are availabe for public view

from 335

from 335

Abstract

Genetic factors have become incredslngly 1mport
ant causes for both congenital and acquired
eye disease 1n the pediatric age group.
accurate statistics are not available.
timated that at least 50% of new cases
Although
1t lS esot
.!~9_ct_I
blindness ln the pediatric age group can be attributed
to genetic causes.
The heredity bases of diseases that affect
the eye Include all three broad categories:
chromosomal aberration. s1ngle gene mutations consis
tent with Mendelian inheritance patterns, and
multifactorial Inheritance; monogenic disorders
can be divided into those that only affect the eye
and ocular adnexae, and those that are mult1system.
Geneocopies. similar physical character1st1cs
caused by different genetic mechanisms, complicate
the evaluation of many genet1c d1sorders
of the eye, including microphthalmia and retin1t1s
pigmento::sa (84t61Jttn~ 1.98.3).
AIM OF WORK
ThiS study lS made to show the role of
genetics (and cytogenetics) 1n the d1agnosis dnd
classlflcation of ocular congenital d1sorders.