الفهرس 
Introduction
Cardiac Surgery and BleedingOnly 14 pages are availabe for public view
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Abstract
Blood loss remains a major problem in cardiac surgery.Intravenous antifibrinolytics are the gold standard for blood conservation during cardiac surgery, but combined local and IV TXA administration may offer superior hemostasis while decreasing side effects.
The aim of this study is to examine the effectiveness of local and/ or systemic application of tranexamic acid during valvular heart surgery as regard perioperative hematological parameters, intraoperative and postoperative blood loss, intraoperative and postoperative transfusion requirements, as well as the possible side effects that can happen in the perioperative period.
Regarding to intraoperative blood loss, it was less amount in group S and group SL in comparison to group C but with no significant difference between group S and group SL
Postoperative blood loss in group SL was less than postoperative blood loss in group S and group C with significant statically difference .
We concluded that combined administration of local and IV TXA by dose mentioned above provides a satisfactory control of postoperatively blood loss in valvular heart surgery.