الفهرس 
Overview of stem cellsOnly 14 pages are availabe for public view
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Abstract
Summary and Conclusion
esenchymal stem cells (MSCs) are the most promising seed cells for cell therapy and tissue engineering, which can be isolated from various sources of human adult tissues such as bone marrow and adipose tissue. However, cells from these tissues must be obtained through invasive procedures and sometimes the individual difference is hard to control. Hence, the search continues for an ethically conducive, easily accessible and controllable source of stem cells. The human endometrium is a unique tissue that undergoes regular dynamic processes of growth, differentiation, sloughing, and renewal during a woman’s reproductive years. It not only maintains and affects the normal menstruation but also plays a vital role in female fertility.
Many studies showed that mesenchymal stem cells found in the human endometrium play a very important role in cyclic regeneration in the human endometrium and their damage leads to a thin dysregulated endometrium incapable of supporting embryo implantation.
The present study aimed to prove the presence of mesen- chymal stem cells in normal human endometrium.
We collected 15 normal endometrial samples under complete aseptic condition and were sent to the lap where they left in collagenase enzyme for 24 hours then the supernatant
centrifuged and the resultant cell bellets were cultured in
complete media and incubated in suitable conditions in CO2
incubator for several days.
Mesenchymal stem cells were identified morphologically by microscopic examination and by immunohistochemistry to identify surface markers of mesenchymal stem cells.
Culture supernatant were examined several times for CA125 to exclude pathological endometrium.
The current study results concluded the presence of spindle shaped cells expressing mesenchymal stem cells surface markers in normal human endometrium