الفهرس 
MATERIALS AND METHODS
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Abstract
In the present work we used Human foetuses duri~ng
different periods of gestation, ranging from 2% month to
full term. The age of the foetus was approximately
determined either by its length or by the number of Hissed
periods. All adrenal were removed fresh pest mortum and
paraffin sections were prepared. Then the following stains
were used.
Hx. 8 E.
Mallory Azan stain.
Wilder reticular stain.
Periodic acid schiff.
Ammoniacal silver nitrate intensification of
chromaffin reaction.
The present work showed that the microscopic picture
of the Human foetal suprarenal gland differ from the
appearance of that of the adult gland.
At the age of 2% month the gland was defined, large
in size and formed of :
True cortex : Outer thin zone of cells.
FoetaJ. cortext Inne% wide zone which constituted
about 80 % of the whole cortex.
Immigrating sympathochromaffin cells.In the early months of gestation the foetal cortex
formed of large polygonal cells with acidophilic cytopl:3.sm
and large vesicular nuclei.
At the ~~ month of prenatal life degenerative
changes in the form of vacuolation started to appear in
the foetal cortex.
At the s1h and 9~h month the degenerative changes
became massive in the form of Haemor~h~e~ necrosis and
vacuolation.
The permanent cortex in the ~ anQ }rd months was
a subcapsular thin zone of packed cellSl While in the
last two months of gestation its cells became less packed,
with distinct outlines. Prolefiration of the inner layers
of the permane.nt cortex occured to replace the degenerating
cells of the foetal cortex.
The foetal suprarenal gland was invaded by immigrating
sympathochromaffin cells in the form of Islands inbetween
the cells of the foetal cortex. Tl1e immigration was
very active during the 4!h month, while at the &th and ~!~
months the cells tend to be arranged in groups around the
central blood spaces.dal:’k nuclei 1 frequently found with rterve fibers
and arranged in rosette shape. These cells v1ill
form the future neuroblast.
- Few larger irregularly shaped cells which gave
positive chromaffirte reaction at the 6th month.
The framework of the gland in the early months of
prenatal life was formed of very thin connective tissue
capsule 1 from which no trabeculae were arose. Later
during the foetal life the COlli’ective tissue capsule
became more thickned, formad mainly of colJ.agenous and
Reticular fibers, also connective tissue trabeculae were
extended into the substance of the gland.