الفهرس 
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Abstract
The writer wishes to express her deepest gratitude to Prof. Dr. Hasan M. Yusef for his sincere interest and supervision throughout the study and also his great help in editing the manuscript Greateful thanks are due to Prof. Dr. Sanaa Omar for suggesting the topic of the thesis, for her continuous encouragment, tremendous help, her guidance in the execution of the experimental work and for the supply of the references Thanks are also expressed to Prof. Dr. A.F. Abdel- Fattah of the National Research Centre at Giza for guidance and criticism of the manuscript throughout the preparation Thanks are also due to Prof. Dr. H.J. Rehm, Director of the ”Institut für Mikrobiologie, Westfalische Wilhelms-Universität, Münster, Germany” for supplement- ation with the experimental organisms and most of the chemicals used in this investigation.