الفهرس 
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Abstract
Preterm delivery occurs in 5–13% of pregnancies . Preterm delivery is a major cause of perinatal morbidity and mortality (Martin et al., 2010). Most of the damage and death cases occur in infants delivered before 34 weeks
There are different methods used for predicting preterm birth including the cervical morphology and biometry , electromyography, Doppeler study of uteroplacental circulation and biomarkers (like assessments of salivary estriol, fetal fibronectin (FFN), maternal serum alpha fetoprotein (MS-AFP), cervicovaginal intracellular adhesion molecule-1 (ICAM-1), phosphorylated insulin-like growth factor binding protein-1 (phIGFBP-1), cervicovaginal beta-human chorionic gonadotropin (β-hCG) and serum level of P53) .
100 patients high risk for preterm labor were included in this prospective study , these women were selected from the attendants of Obstetrics Outpatient Clinic of El-Minia University Hospital, Egypt during the period from from the first of January, 2012 to the last of December, 2014 .
Cases selected for this study were subjected to:
1) Transvaginal cervical sonography
2) Power Doppler study of the uterine artery to detect any abnormality
3) Electromyography
4) Measurment of serum P53 level
The aim of this study to compare the diagnostic and predictive values of ultrasonographic parameters , Doppler indices , EMG and serum P53 level used in this study for prediction of preterm labor < 35 weeks.
In our study we found that forty two cases of the total number of cases in the study developed PTL before 35 weeks , 15 cases ( 35.8 %) of them had history of previous PTL, 15 cases (35.8 %) had symptoms suggesting threatened PTL , 5 cases ( 12 %) had previous of 2nd trimester abortion 5 cases and 7 cases had both history of previous PTL and symptoms suggesting threatened PTL ( 16.4 %).
In the study 22 cases have short cervix (cervical length < 2.5 cm ) measured by transvaginal ultrasonography , only 14 cases of them delivered at < 35 weeks while 8 cases delivered at ≥ 35 week gestational age , there is significant difference among women delivered at < 35 weeks VS ≥ 35 week gestational age and to predict delivery <35weeks, cervical length <2.5 cm had a sensitivity, specificity, PPV, and NPV of 33.3 %, 68.2 %, 63.2 %, and 64.1%, respectively.