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Abstract Despite the well-documented risk factors and health consequences of postpartum depression, it often remains untreated and undetected. Very few studies have comprehensively examined this problem in Upper Egypt, knowledge of these factors may help identify those who are at higher risk and can benefit -#102;-#114;-#111;-#109; early professional help. The aims of the present study were to estimate the prevalence of postnatal depression, identify the variables associated with the risk of postpartum depression and raise the awareness of nurses regarding the problem of postnatal depression. Subjects and Methods: Potential subjects for this study were women who gave birth between first of October 20 II to the end of March 20 l2, at 3 sites in the outpatient departments of Sohag university hospital, as well as two randomly selec-#116;ed MCH centers at Sohag; AL-Shahead MCH center and Dar Alsalam MCH center. Screening for PPD was conducted at clinic sites during the standard 6week postnatal visit. All postpartum women were subjected to semi structured interview using a structures interviewing sheet. In addition to the psychiatric measures using EPDS, postpartum Depression Predictors Inventory (POP I), Edinburgh Postnatal Depression Scale and Nurse’ knowledge questionnaire sheet. Results: low educational and income level, and poverty and multiparity are the major risk factors for PPD (87.3 %, and 85.5 %). Failed attempt of breast feeding, lack of perceived social support for the pregnancy -#102;-#114;-#111;-#109; husband, family and friends (68.0%,70.5%, 64.2%), unemployment of the mother or head of household (88.0%), Lack of emotional and financial support -#102;-#114;-#111;-#109; the husband, prenatal depression, in particular, was a strong predictor of PPD (d=0.75) marital conflict (85.8%) as well as stressful events in the previous 12 months (89.6%) together with unwanted pregnancy, are also predictors for PND. The nurse’s knowledge scores at the pre-test were low for the definition, prevalence, symptoms of PND, presence of PND tests (22.9%, 5.7%, 34.3% and 60 % respectively). At the post test it rose up to (82.9%, 57.1 %, 91.4% and 100 % respectively). It can be concluded that: In accordance with other studies, socioeconomic, biological, social and psychological risk factors are involved in the development of PND; the implementation of the program was associated with high significant improvement in maternity nurse’s knowledge in one month post-program in comparison to that in pre-program. It is recommended that; attending a support group is a common treatment preference and a major maternal help- seeking facilitator was education about postpartum depression, to women and nurse midwives through the periodic health education programs. |