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Abstract In this study, the result suggested that garlic extract has antibacterial effect against E. coli and S. aureus at different concentrations. MIC of garlic extract against E. coli and S. aureus was 10 mg/ml and 1.25 mg/ml respectively. In ex-vivo study, there was no cell morphological changes have been observed at any interval post culture in the tested groups after garlic consumption by chickens. The phagocytic percentage was high in garlic treated group in comparison with garlic untreated group. The phagocytic percentage was 63.3% in the 1st day of the feeding of garlic extract compared to 50.5% in the control group at the same day. At 7th, 14th and 21 days, the phagocytic activity increased and it was more than 95% at these intervals in the test group compared to about 52% in the control group. The bactericidal activity of cells from garlic treated group after 24 h, 7 days, 14 days and 21 days were 52%, 97.2%, 86.7% and 95.6% respectively compared with 50%, 60%, 16.7% and 92% of cells from garlic untreated group. Nitric oxide (NO) production of cells from garlic extract treated animals was less than that of control untreated animals cells. The NO production of cells from garlic extract treated animals after 24 h, 7 days, 14 days and 21. |