Search In this Thesis
   Search In this Thesis  
العنوان
MRI Guided High Intensity Focused Ultrasound (HIFU) in the Management of Uterine Fibroids /
المؤلف
Helal, Rania Abdelnasser Mohamed Abdelhaleem.
هيئة الاعداد
باحث / Rania Abdelnasser Mohamed Abdelhaleem Helal
مشرف / Maha Abdel Meguid El-Shinnawy
مشرف / Ahmed Mohamed Osman
مناقش / Ahmed Mohamed Osman
تاريخ النشر
2015.
عدد الصفحات
152p. :
اللغة
الإنجليزية
الدرجة
ماجستير
التخصص
الأشعة والطب النووي والتصوير
تاريخ الإجازة
1/1/2015
مكان الإجازة
جامعة عين شمس - كلية الطب - الاشعة التشخصية
الفهرس
Only 14 pages are availabe for public view

from 32

from 32

Abstract

Summary Fibroids are the most common benign uterine tumors in women of reproductive age. Associated symptoms include dysmenorrhea, spotting, hypermenorrhea, anemia, lower abdominal pain, pressure on adjacent organs and disorders of micturition and defecation. The common treatment modalities for symptomatic women are hysterectomy or myomectomy. However, these surgical procedures are associated with morbidity in many cases, and involve at least several days of hospitalization as well as several weeks of convalescence. The high incidence of symptomatic uterine fibroids and the high cost of surgical interventions and their sequelae create a significant financial burden that has stimulated the search for alternative approaches. Treatment of fibroids using high-intensity focused procedure is applied transcutaneously. In this procedure, the fibroid is gradually heated under continuous MRI monitoring in small, focused stages, until temperatures > 55 °C are reached to achieve complete denaturation of the localized tumor. The high energy concentration in a very small, ellipsoid focus to create discrete areas of tissue necrosis preserves both adjacent tissue and the structures between the energy source and the target tissue.
Conclusion MRgFUS treatments continue to advance as experience with the technology grows and technical improvements are made. As a result, treatments will likely become more effective and will include a larger subset of patients with symptomatic leiomyomas. As more long-term follow-up data are published, the efficacy of this technique can be further compared to more invasive surgical and minimally invasive catheter treatments.