الفهرس 
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Abstract
The loss of residual renal function in patients with end-stage renal disease has important clinical manifestations. This includes adverse effects upon volume control and patient survival. Among both peritoneal dialysis and hemodialysis patients, continued residual renal function is associated with improved survival.
Both volume expansion and the high urea load per nephron are rapidly reversed by dialysis of any form. Therefore, many patients have a marked reduction in, or even cessation of, urine output when dialysis is instituted.
Mortality and RRF decline tends to be greatest among all diabetics regardless of dialysis modality. DM has been well described in observational studies as a risk factor for loss of RRF in many PD cohort studies. Whether the higher risk of death among the diabetics may be explained by a more rapid loss of residual GFR observed among the diabetics is unexplored.
This study was done to evaluate the rate of loss of the RRF between diabetic & non diabetic ESRD patients on hemodialysis.
This study was done on newly diagnosed 60 ESRD patients of 18 years old & older, 30 of them were diabetic & 30 were non diabetic. Demographic & baseline data were obtained 0-4 weeks before the start of chronic dialysis treatment.
During follow-up, data were collected at fixed time points 3,6 & 12 months after the start of dialysis.
There was a significant difference in the RRF between the diabetic & non diabetic groups; the eGFR of the diabetic group at the end of the study was 6.6+1.1 ( p value = 0.161) while that of the non diabetic group was 9.3+1.6 ( p value = 1.000)
This indicates the relationship between diabetes mellitus & the loss of residual renal function in patients on hemodialysis.