الفهرس | يوجد فقط 14 صفحة متاحة للعرض العام |
المستخلص This work was conducted to clarify the possible therapeutic effect of Carica papaya pulp and seeds as obtained from mature and unripe fruits on the renopathic rats . a total number of Sprague Pawley male albino rats (60 rats), (135-155g) each were used in this study . the rats distributed on 10 groups (6 rats each) the first main group negative control fed for (42 days) on the basal diet , while the other main group inflicted firstly with gentamicin (100mg /1000g from body weight ) renopathy , then distributed on 8 group (6 rats) each. the first renopathic group fed on the Basel diet for (42) days and considered as positive control group while was fed on the Basel diet other renopathic groups fed on either mature or unripe papaya pulp (5% or 10 %) , or seeds (5% & 10 % ) of either mature or ripe fruits the feed intake calculated each day while body weight (and accordingly body weight gain BWG) calculated each week , and urine collected at the end of the experiment, rats sacrificed, serum obtained and biochemical analyses carried out . histopathological investigation carried on the tissues of the results arrived at world be sum analyzed in the following: 1. Body weight gain (BWG%) , feed intake, (FI) and fed efficiency (FER) pronouncedly reduced due to renopathy, then raised when inflicted rats papaya fed on papaya pulp and seeds. 2. Papaya seeds diet revealed higher improvement of BWG%, FI and FER than pulp diet, provided that improvement was dose dependent the more concentration of papaya seeds in diet the more the level of BWG% and FER . 3. Best treatment seems to be that of the papaya seeds diet 5% & 10% showing highest BWG% and FER. |