الفهرس 
INTRODUCTIONOnly 14 pages are availabe for public view
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Abstract
The trend of the last decades has been to base clinical decision making more and more on sound scientific evidence, i.e., evidence-based medicine .In practice this has led medical specialists to develop evidence-based clinical practice guidelines (CPGs) for promoting standard of medical care. Worldwide, a number of organizations such as CBO (Dutch Institute for Health Care Improvement) in Netherlands and SIGN (Scottish Intercollegiate Guidelines Network) in Scotland have been founded to assist specialists groups and general practitioners in the development of guidelines. In 2002 the Guidelines International Network (G-I-N) was founded to promote systematic development of CPGs through international collaboration.
Recently the AFM-EBCPGs (Alexandria University Faculty of Medicine for Evidence –based Clinical Practice Guidelines) in Egypt have been founded in 2009 to proceed with the same endeavors in the field of guidelines and became a member of the G-I-N.
One way to reduce the cost and time, avoid unnecessary duplication of effort of guideline development ,avoid variations of institution setting, such as type of practice and location, consider availability of resources, respect difference between patient populations, respect local policies, and practice patterns is by relying on local adaptation of guidelines developed at the (inter)national level by expert groups.
Therefore clinical guidelines developed by government agencies or medical specialty organizations at the national level usually need to be adapted to fit the local practice before they can actually used by clinicians at specific institution and successful guideline implementation has to be supported by organizational efforts.
The aim of this work was to adapt evidence based clinical practice guideline (EBCPG) on diagnosis and treatment of acute bronchiolitis in infants below 2 years of age that could be applied in the local or the national context to improve health practice.
A retrospective study conducted on medical records of infants and children (one month up to 2years) during the year of 2013 for evaluation the current situation in diagnosis and treatment of those cases and the need for guidelines in this topic.
Our panel has used some criteria to identify the high-priority topic including its prevalence, associated burden ,practice variation, likelihood that the adapted CPGs will be effective in influencing practice, the potential for improvement the quality of care and/or patient outcomes and the existence of relevant good-quality source evidence-based CPGs available for adaptation.
The panel has selected the ADAPTE process for Guideline adaptation with its resource toolkit as their methodology.
The process started by retrieving fourteen source CPGs which then reduced to only three CPGs (the other CPGs were excluded because they did not answer all health questions done by the panel or their language is not English language or not evidence based), then the selected guidelines were processed throughout the ADAPTE assessment tool and at the end, we used three source CPGs for the adapted CPG (Scottish Intercollegiate Guidelines Network (SIGN) Bronchiolitis in children: A national clinical guideline 2006, American Academy of pediatrics (AAP) Clinical Practice Guideline: The Diagnosis, Management and Prevention of Bronchiolitis 2014, and Southern Health Clinical Practice Guideline for the Management of Bronchiolitis in Infants and Children 2006).
A draft adapted CPG was produced and reviewed by the external review group from AUCH staff and Ministry of Health.
Plan for updates were stated to be after 5 years and proposed plan and tools for implementations were stated in the adapted CPG.