الفهرس | Only 14 pages are availabe for public view |
Abstract Ischemic stroke is a wide spread disease affecting large number of population and causing a great mortality and morbidity with the accompanying social, psychiological and economic problems. Carotid atherosclerosis has been associated with increased risk of stroke and poorer cognitive performance in older adults. An important cause of stroke is the transformation of a quiescent carotid artery atherosclerotic lesion into an unstable morphology, which becomes vulnerable to rupture and thromboembolism. It is hypothesized that (HGF) may play a role in the natural history of atherosclerosis and hence the pathogenesis of cardiovascular diseases , including ischemic stroke. we conducted the present study to determine the relation between the level of circulating (HGF) and carotid vessel atherosclerosis in ischemic stroke , and if it differs between stroke subtypes ( Atherothrombotic versus Cardioembolic). Also to answer the question if (HGF) could serve as an indicator of stroke severity & its role in the prognosis. This study was conducted on (100) acute ischemic stroke, enrolled from Neuropsychiatry department, Menoufia University Hospital. The patients were 2 groups (carotid atherosclerosis & cardioembolic). |