الفهرس 
INTRODUCTION AIM OF THE WORKOnly 14 pages are availabe for public view
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Abstract
Breast-conserving therapy has not been widely considered for women with subareolar carcinomas due to increase risk of local recurrence owing to inadequate margins of resection or to poor cosmetic results.
The present study was designed to standardize clinicopathological criteria for nipple and areola infiltration in patients with subareolar breast carcinoma in a consecutive series of mastectomy specimens.
from this study it is concluded that surgical treatment of subareolar breast carcinoma that preserves NAC might result in leaving a malignant focus in about 22% of cases even with relatively small tumours when; (I) the age of the patient is 50 years or less, (2) the tumour is located within two centimeters from the nipple-areolar distance regardless the size of the tumour, (3) the histological type of the tumour is invasive ductal carcmoma or invasive ductal with extensive intraductal components.
Local treatment of breast cancer should involve a collaborative effort between surgeons, radiologists, pathologists,
and medical oncologists all working with the patient.