الفهرس 
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Abstract
The burden of cancer is increasing across the world and thus it is the leading cause of deaths in economically developed countries and the second leading cause of deaths in developing countries. Cancer is the uncontrolled growth and spread of cells. It can affect almost any part of surrounding tissue and can metastasize to distant sites. swth often invadethe body. The groMany cancers can be prevented by avoiding exposure to common risk factors, such as tobacco smoke. In addition, a significant proportion of cancers can be cured, by surgery,tobacco smoke. In addition, a significant proportion of cancers can be cured, by surgery, .rapy or chemotherapy, especially if they are detected earlyradioth This part includes a brief literature review on the anticancer activity of different tetrahydronaphthalene derivatives regarding their mechanism of action. In addition, different chemical methods adopted for the synthesis of different tetrahydronaphthalene derivatives are discussed.